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Background: Satraplatin is the 1st orally bioavailable platinum anticancer drug.
Objective: Our objectives were to evaluate efficacy in vitro against a canine cancer cell line, to determine the maximally tolerated dose (MTD) of satraplatin in tumor‐bearing dogs, to identify the dose‐limiting and other toxicities in dogs, and to record pharmacokinetics (PK).
Animals: Dogs with macro‐ or microscopic...
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