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Breast cancer is the second leading cause of cancer deaths in women in the U.S. Two main problems appear to affect the decision of detecting and diagnosing breast cancer: the accuracy of the CAD systems used, and the radiologists' performance in reading mammograms. The main challenge in designing any CAD system is to maintain a high sensitivity level in detecting the abnormalities as the density of...
Breast cancer is the most common cancer in many countries all over the world. Early detection of cancer, in either diagnosis or screening programs, decreases the mortality rates. Computer Aided Detection (CAD) is software that aids radiologists in detecting abnormalities in medical images. In this article we present our approach in detecting abnormalities in mammograms using digital mammography. Each...
The presence of lymphocytic infiltration (LI) has been correlated with nodal metastasis and tumor recurrence in HER2+ breast cancer (BC). The ability to automatically detect and quantify extent of LI on histopathology imagery could potentially result in the development of an image based prognostic tool for human epidermal growth factor receptor-2 (HER2+) BC patients. Lymphocyte segmentation in hematoxylin...
In this paper we discuss a new approach for the detection of clustered microcalcifications (MCs) in mammograms. MCs are an important early sign of breast cancer in women. Their accurate detection is a key issue in computer aided detection scheme. To improve the performance of detection, we propose a Bagging and Boosting based twin support vector machine (BB-TWSVM) to detect MCs. The algorithm is composed...
Automated detection and segmentation of nuclear and glandular structures is critical for classification and grading of prostate and breast cancer histopathology. In this paper, we present a methodology for automated detection and segmentation of structures of interest in digitized histopathology images. The scheme integrates image information from across three different scales: (1) low- level information...
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