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C-reactive protein (CRP) is an acute phase reactant, and is an important biomarker whose concentration in serum can be used for monitoring inflammation and predicting atherosclerotic, cardiovascular events etc. In this study, surface plasma resonance (SPR) technology is adopted in combination with immunoassay for CRP concentration analysis and dynamic observation in limited time frame, thereby eliminating...
A novel strategy is proposed to greatly reduce the volume and cost of a time-resolved fluorescence detection system. Laser diode is employed as a replacement for ultra-fast DPSS lasers that are expensive and bulky, thus facilitating implementation in microfluidic chip platforms. Besides, corresponding noise-reduction strategy is provided. This method paves way for ultra-sensitive detection of HIV-1...
A droplet-based microfluidic system was developed for biochemical assays of triglycerides and methanol as potential applications in medical rapid diagnostics and food safety. We present a novel platform to manipulate biology reaction droplets with features of self-moving, self-mixing, and self-positioning toward the detection spot. The driving force comes from the gradient of surface tension force...
The concept of biosensor with imaging ellipsometry was proposed about ten years ago. It has become an automatic analysis technique for protein detection with merits of label-free, multi-protein analysis, and real-time analysis for protein interaction process, etc. Its principle, and related technique units, such as micro-array, micro-fluidic and bio-molecule interaction cell, sampling unit and calibration...
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