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D-serine is a glial neuromodulator that is linked to several brain disorders such as schizophrenia, epilepsy, or stroke. We have developed an in situ D-serine microbiosensor that consists in a cylindrical platinum microelectrode covered with a layer of D-amino acid oxidase from the yeast R. gracilis. This enzyme converts D-serine into hydroxypyruvate, while producing hydrogen peroxide that, in turn,...
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