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Poly(acrylic acid) (PAA) was attached on both termini of Pluronic P85 copolymer (EO 27 PO 39 EO 27 ) via atom transfer radical polymerization (ATRP) to produce a novel block copolymer, PAA-b-P85-b-PAA (P85PAA). The P85PAA–DOX complex formation and drug loading were strongly dependent on the PAA segment length and pH, where the protonation of carboxyl groups in the PAA segment...
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