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Mantle cell lymphoma (MCL) is a rare, often aggressive type of B‐cell lymphoma with poor survival and no cure. Cancer and cancer treatment has a negative impact on health‐related quality of life (HRQOL) both during active disease and in the long term, and improvement of HRQOL is a crucial objective of cancer therapy in older patients and no curative intent. Baseline HRQOL has in other lymphoma populations...
BackgroundElderly patients with diffuse large B‐cell lymphoma (DLBCL) have an inferior prognosis, due in part to advanced age and pre‐existing comorbidities, with reduced tolerability and deliverability of standard R‐CHOP chemotherapy.
AimsTo examine the deliverability, toxicity and efficacy of R‐CHOP and the prevalence of the germinal and non‐germinal phenotype DLBCL in an elderly Australian cohort...
BACKGROUNDAlthough the combination of rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R‐CHOP) is considered standard therapy for diffuse large B‐cell lymphoma (DLBCL), patterns of use and the impact of R‐CHOP on survival in patients aged >80 years are less clear.
METHODSThe Surveillance, Epidemiology, and End Results (SEER)‐Medicare database was used to characterize presentation,...
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