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In total hip arthroplasty, a placement of stem, which is one of the parts of the artificial hip joint, is even difficult for skilled operators. An optimum location of stem is different for each patient. No system for specifying the optimum location has been established. We pay attention to the method using ultrasound in consideration of portability and high introduction ratio to the medical field...
Long term reliability has been a challenging issue in CMUT probe development. Kolo Medical Inc. has worked on improving reliability of CMUT probes for many years. Testing methods were developed and utilized to assess long term reliability and evaluate CMUT design improvements. A large amount of long term reliability test data were collected and analyzed.
The aim of this study is to investigate how the intracellular ROS responds to different degrees of sonoporation. Using a customized platform for 1.5-MHz ultrasound exposure (13.33-μs duration and 0.70-MPa peak negative pressure) and observing the dynamics of sonoporation and intracellular ROS at the single-cell level, we quantified the exogenous molecular uptake and intracellular ROS indicator to...
A novel ultrasound (US) platform with high channels density is a pre-requisite to open new frontiers in diagnostic and/or therapy by experimental implementation of new enabled advanced techniques. To date, few systems in the world permit to have a full and simultaneous control both in transmit and receive of all single elements of arrays with more than 1000 transducers. This paper presents a powerful...
A transparent transducer array is desired in backward-mode photoacoustic imaging (PAI). CMUT technology is especially suitable for this application because of its wide bandwidth and a wide selection of processing materials. We have previously demonstrated a single-element CMUT with an ITO bottom electrode for improved transparency. The device showed 40% to 70% optical transmission from 700 nm to 900...
Because conventional geophysical measurements cannot directly measure the microstructure or pore fluids of rocks, new measurement approaches are needed as well as one that can target regions of interest. The aim of this study is to utilize the nonlinear interaction of two co-propagating longitudinal waves to characterize induced viscoelastic changes occurring in the rock microstructure. Our experimental...
The heart, like skeletal muscles, is made up of muscular cells arranged regularly and packed into sort of bundles commonly called cardiac fibers. After a myocardial infarction (MI) both during the acute phase and the reperfusion of the myocardium, several cells die and some local fibers orientation modifications appear. Consequently, the heart does not contract properly anymore. The evaluation of...
The article deals with the comparison of different detection methods suitable for reinforced concrete structures. The main request for the detection method is the reliability of finding cracks formed in the concrete, which is expected to breach before the reinforcement material such steel, plastic, or glass. This breach occurs due to significantly lower concrete tensile strength in comparison with...
It is common knowledge in the medical field that fingernails may potentially be a useful biomarker in assessing certain disorders of the body by both their appearance and texture. With the use of a hand-held, portable ultrasonic device a user may have the ability to quantitatively assess the progression of fingernail properties on-the-spot and over the long term. This device would be applicable to...
Kolo Medical Inc. has developed a 10 MHz 1.5D array probe using CMUT technology. The probe has 192 × 3 elements and a bandwidth covering from 4 MHz to 17 MHz. The probe does not require any switches to control elevation aperture size by utilizing DC bias. With ultra-wide bandwidth and 1.5D array, the probe is a one-probe solution to replace two or three linear array probes in clinical applications.
A wide spectrum of methods is used to image brain activation in vivo, such as functional MRI (fMRI) or positron emission tomography. Both techniques have excellent depth penetration but do not provide good spatial nor temporal resolution. By contrast, ultrasound imaging achieves good spatiotemporal resolution in depth, but until now its poor sensitivity has limited its use to the imaging of major...
This paper compared the performances of the surface electromyography (sEMG) with Ultrasound(US) signals in finger motion recognition. Compared to traditional sEMG-based human machine interface (HMI), the ultrasound can provide some information about the morphological changes of muscles and has higher resolution. It is possible for the US-based HMI to recognize some more dexterous hand gesture especially...
The quality of ultrasound images highly depends on sonographer skills. This paper describes a platform for the reduction of operator dependency during transabdominal ultrasound examinations. The design includes a linear system to enable automatic transabdominal ultrasonography of the cervix. The system was integrated within APLIO MX SSA-780A TOSHIBA ultrasound machine. Results show operator independent...
Transesophageal echocardiography (TEE) involves the use of an ultrasound transducer mounted at the tip of an endoscope to make ultrasonic images of the human heart from the esophagus. In conventional TEE probes, each transducer element is wired-out by a micro-coaxial cable to an external imaging system. To obtain real-time three-dimensional images, however, a two-dimensional transducer array with...
The hip joint center (HJC) location is required for calculation of hip kinematics in various applications. The functional method utilizes the movement of femur with respect to acetabulum to find the location of the center. A popular way for measuring this movement is through an optical motion capture system. This method is fast and economical for most applications where we require an instant HJC even...
Rotary driving of a single micro/nano object is an important technology in assembling of micro/nano structures, handling of cells and other biological samples, micro/nano measurement etc. In 2013, our research group reported a method to rotate a single nanowire around a fiberglass in water. Based on the experiments, the rotary driving is caused by the acoustic streaming eddy around the micro manipulation...
One in 11 Americans has experienced kidney stones, with a 50% average recurrence rate within 5–10 years. Ultrasonic propulsion (UP) offers a potential method to expel small stones or residual fragments before they become a recurrent problem. Reported here are preliminary findings from the first investigational use of UP in humans. The device uses a Verasonics ultrasound engine and Philips HDI C5-2...
The high capacity of modern wheel fabrication plants and high demands on the detection sensitivity for internal defects in railroad wheels along with the need to perform an objective and well documented ultrasonic inspection require the application of automated systems which are integrated into the production line. The paper offers a description of the technology of a fully automated system jointly...
In this paper, we propose a new modality for automated diagnostic assessment of tissues in the context of Duchenne Muscular Dystrophy (DMD). In this force-correlated ultrasound imaging method, we first perform an automated extraction of a multitude of ultrasound images captured across a range of contact forces — a force video, or a force sweep. These images are then coupled with a mechanism to enhance...
In this paper, we present a technique for quantitative discrimination of Duchenne Muscular Dystrophy (DMD). Our ultrasound image data is generated with a novel force-controlled ultrasound acquisition system that allows precise ultrasound image acquisition at a predetermined force. We use the texture of ultrasound images, as calculated by the Canny edge detector, as the input image feature for our...
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