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Hyperglycemia is frequently found (40–60%) after all kinds of stroke and it has been related to increased lesion size and poor clinical outcome. In this chapter, we will primarily focus on ischemic stroke; we will outline the incidence and natural course of post-stroke hyperglycemia and discuss the possible etiologies of post-stroke hyperglycemia. Subsequently, we will present an overview of various...
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in women in the USA. Women with diabetes are at a greater risk of CVD than men with diabetes. In this chapter we review the various mechanisms by which hyperglycemia potentiates this increased CVD risk, including coagulation abnormalities as well as endothelial dysfunction. Where applicable, sex-specific differences in these...
This chapter discusses the key findings from the literature regarding stroke incidence in patients with diabetes (DM), DM-specific and non-specific risk factors of stroke in the diabetic population, course and outcome of stroke in subjects with DM, and the peculiarities of type, site, and size of stroke in diabetic patients. The results of major clinical trials aimed at correcting hyperglycemia, hypertension,...
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