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Die Naturstoffklasse der Chlorotonile besitzt eine exzellente Wirksamkeit gegenüber multiresistenten Gram‐positiven Bakterien und Plasmodium falciparum. Die bisherigen Vertreter dieser Wirkstoffklasse besitzen eine schlechte Wasserlöslichkeit und kaum orale Bioverfügbarkeit, jedoch konnten wir kürzlich Fortschritte bei der Verbesserung dieser Eigenschaften erzielen. Mittels weiterer Funktionalisierung...