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In this work, the effect of gold nanoparticles (AuNPs) with diameters of around 5, 10 and 20 nm on PCR efficiency is evaluated respectively using a real-time PCR machine. Gold nanoparticles show no obvious effect on PCR at low particle concentration. When the concentration is increased, PCR inhibition is observed. At the same particle concentration, gold nanoparticles of different sizes show different...
Optical microscopy is an indispensable tool for obtaining spatial and temporal resolution within living cells and tissues. In this paper, a novel multiphoton microscopy technique which exploits the third-order nonlinearity called four-wave mixing and applied to gold nanoparticles in resonance with their surface plasmon is developed. The coherent, transient and resonant nature of this signal allows...
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