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Today, biomedical devices have become an issue where system manufacturers are working intensively. At present, many domestic and foreign biomedical companies offer various EMA products. Electromagnetic fields (EMF) has a significant impact on our body. These fields are being used for bone problems, cartilage regeneration, and pain removal for physiotherapy purposes. Lately, EMFs are often used in...
Dynamic mechanical analysis (DMA) was carried out to understand the effect of the application of elastin on wound skin of hairless mice. Wound group, placebo group, and elastin group were selected to evaluate that effect. As the results of DMA testing, the wound and the placebo groups showed lower storage and loss moduli than the elastin group. On the result of loss tangent, there is a small difference...
Diabetic Foot Ulcer (DFU) is a major complication of Diabetes, which if not managed properly can lead to amputation. DFU can appear anywhere on the foot and can vary in size, colour, and contrast depending on various pathologies. Current clinical approaches to DFU treatment rely on patients and clinician vigilance, which has significant limitations such as the high cost involved in the diagnosis,...
Plasma is the fourth state of matter. For long time plasma has been used in several areas of science. Moreover, plasma in medicine has a huge area from wound healing to sterilization of medical equipment. One of the most promising applications of cold plasma is on wound healing. The aim of this study is to develop a portable atmospheric cold plasma device for infected wound management. This study...
Wound infection care after clinical surgery is mostly done by human observation. This type of work not only adds extra work to clinical physician and/or nurses, but is also subjective in nature. Doctors are relying on off-premise post-surgery monitoring mechanism to track the progress of their patients. This paper introduces our scheme to assist doctor in post-operative wound analytics based on smart...
The wound care management of bedsore is important to long-term bedridden patients. The wound size is usually monitored by a consumer-graded camera and then calculated by computer-aided analysis. In this paper, we simulated a subcutaneous and dermal injury using vacuum cupping experiment and performed multispectral imaging with three wavelengths, including active 650 nanometers red light and 940 nanometers...
Novel hydrogel scaffolds were prepared in the aim to obtain materials with tailored properties for biomedical applications, especially for skin tissue repair and engineering. The influence of the initiating parameters of synthesis on the physical and chemical properties, as well as their biocompatibility, was evaluated. Chemically modified chitosan was crosslinked with poly(acrylic acid) (PAA), followed...
Iontophoresis and electroporation are two progressively expanding methods that are used to enhance drug delivery into the human body. They involve the exposure of cells to an external electric field, to drive genetic drugs (plasmid) to a desired location or permeabilize the cell's membranes for the drug to pass. While electroporation has been successful in enhancing plasmid gene therapy in the past,...
Chronic wound healing is an important problem especially in diabetic and the elderly which is needed development of the current treatment methods. Electromagnetic fields (EMF) has a significant impact on our body. These fields are being used for bone problems, cartilage regeneration, and pain removal for physiotherapy purposes. Lately, EMFs are often used in in vitro and in vivo assays. In this study,...
This article describes experimental measurements of a skin temperature in vicinity of a surgical wound. Measurements were carried out in collaboration with the orthopedic department of the University Hospital Olomouc, Czech Republic. A system used for sensing, transmission and visualization of physiological parameters was developed at the University of West Bohemia in Pilsen. A main goal of measurements...
Burn debridement is a challenging technique that requires significant skill to identify regions requiring excision and appropriate excision depth. A machine learning tool is being developed in order to assist surgeons by providing a quantitative assessment of burn-injured tissue. Three noninvasive optical imaging techniques capable of distinguishing between four kinds of tissue-healthy skin, viable...
This papers presents the use of color imaging as a starting point of burn wound evaluation, by the discrimination between healthy skin and burn wound. The skin/burn area identification is performed pixel-wise, according to the properties of an entire encompassing patch. The classification is learned under a supervised scenario, according to a ground truth defined by specialist surgeons from a large...
Low-temperature plasma is useful for the care of wounded skin. It accelerates wound healing. However, the mechanism of this effect has not been fully elucidated yet. Galectins, which are a family of animal lectins having galactose-binding ability, are reported to accelerate wound healing. In the present study to clarify whether or not galectins were expressed during the process of wound healing in...
Low temperature plasma (LTP) has proven to be an effective way in wound healing, skin diseases, sterilization, and so on. This paper presented an atmospheric pressure discharge plasma jet in flowing argon by means of dielectric barrier discharge (DBD). Then, the effects of LTP on skin wound healing of mice in vivo were evaluated. Two wounds of 4 mm in diameter along the both sides of the spine were...
Introduction: iloprost is a recommended treatment for several vascular diseases such as severe Raynaud's syndrome and digital ulcers in Systemic Sclerosis (SS). In vivo reflectance confocal microscopy (RCM) is a non-invasive imaging tool that can evaluate cutaneous microcirculation. The goal of this study was to observe, in real time, the effect of iloprost on cutaneous microcirculation by using RCM...
Diabetes is a type of disease and is much more dangerous. Normal cells in our body divide in orderly and balanced fashion. Diabetes occurs when certain cells begin to grow out of control. Diabetes cells can also spread to other parts of the body through the blood, nerves or lymph system, in a process called metastasis. Diabetes of the cell in the outer most layer of skin called the epidermis. The...
Wound image segmentation of skin area is one of the key steps in automatic judgment, which can help clinicians in their diagnosis. This work is part of the telecare program dedicated to the design of a surgery site infection detection system We proposed a series of image processing steps composed of image processing algorithms and a novel segmentation method of complementary computation. As edge-based...
Quantitative analysis of skin wound is critical in objective evaluation of a therapy. In this paper, a robust wound segmentation method is presented. The proposed method uses gradient vector flow (GVF), therefore, the segmentation is quite stable to variation of color characteristics of a camera used for image capture or illumination.
Burn wounds resulting from thermal insult to the skin are typically classified according to varying depth and therefore require differential levels of medical intervention. In this paper, two methods are proposed for assessing burn injury. The two methods compared are photometric stereo (PS) and spectral analysis. Firstly, PS represents a robust topography recovery algorithm that is implemented to...
The magnetic thermo-sensitive materials such as iron oxide particles and their colloids have been widely studied in local hyperthermia [1, 2]. Some researchers have been tried to apply the composite sheet instead of particles or their colloids to healing of skin infections including hyperthermia-aided immunotherapy [3, 4]. To healing of skin wound or tumor, the temperature over 43°C can create an...
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