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In this Letter, the nanoporous anodic alumina membranes (nanoPAAM) were first fabricated by the two-step anodic oxidisation method, and then based on these nanoPAAM master molds, polymer polymethylmethacrylate nanopillars with controllable heights and diameters were achieved by the direct casting method. Subsequently, combined with the ultraviolet lithography or electron beam lithography, a kind of...
Nanoparticles, as nonviral vectors, have attracted attention for their ability in gene delivery and are currently considered to be prospective future vectors for biological and biomedical application . We prepared organically modified cationic silica nanoparticles toward the high performance nonviral vector. It is to be noted that the complexes of DNA and nanoparticles are regarded as a simple model...
The encapsulation of double-stranded DNA (dsDNA) fragments (158 base pairs, contour length L = 54 nm) by the cationic diblock copolymer poly-(butadiene-b-N-methyl-4-vinyl pyridinium) [PBd-b-P4VPQ] was studied using phase contrast microscopy. The DNA copolymer vesicles were prepared using a single emulsion technique. In this procedure, an aqueous solution containing the short fragment DNA is emulsified...
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