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We showed that 5 μM acetylcholine (ACh) and 100 μM norepinephrine (NE) cause increases in the total Ca2+ content in acinar cells by 30 and 87% and in the exocytosis intensity by 15 and 20%, respectively. Application of 5 μM ACh and 100 μM NE increased the free cytosolic Ca2+ concentration ([Ca2+]i) by 87 ± 2 and 140 ± 7 nM, respectively. Application of ACh and NE in a Ca2+-free external solution...
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