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Superoxide dismutase (SOD) catalyzes the conversion of superoxide to hydrogen peroxide. Heterozygous mice of strain B6;129S7‐Sod1tm1Leb/J were obtained from Jackson Laboratories and bred to produce offspring that were heterozygous (+/Sod1tm1Leb), homozygous wild‐type (+/+), and homozygous knockout (Sod1tm1Leb/Sod1tm1Leb) for the Cu/Zn superoxide dismutase (Sod1) gene. Splenocytes from these mice were...
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