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This work is focused on modelling HIV mutation and drug resistance. We develop a technique to study viral dynamics in a system of m viral strains including mutation between the different strains. Stability analysis of the nonlinear dynamics involving the free virus and its host cell is provided. For the class of model considered, with ??low?? mutation rate, we analytically determine all possible equilibria,...
The partial sequence of Skeletonema costatum proliferating cell nuclear antigen (PCNA) gene was obtained by RT-PCR. A 714 bp cytochrome b (Cyt b) gene fragment of S.costatum was cloned for the first time. Based on the cloned sequences, a FQ-PCR method was developed to detect the S.costatum PCNA and Cyt b gene, respectively. The above method was applied to study the relationship between the S.costatum...
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