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Rationale. The serotonergic (5-hydroxytryptamine, 5-HT) system is extensively implicated in feeding behavior. In recent years, 5-HT receptors have been classified into 14 subtypes, and activation of 5-HT1B and 5-HT2C receptors inhibits food intake in rats. However, the precise functions in local brain areas of these receptor subtypes are unclear. Objectives. Frontal cortex (FC), lateral hypothalamic...
One possible mechanism by which food consumption signals feeding centers is through the resulting changes in amino acid profiles in the brain. In this study we examined the effect of voluntary consumption of a 50% protein diet or a 0% protein (carbohydrate) diet on extracellular amino acid profiles in the hypothalamic paraventricular nucleus (PVN) of freely moving rats from 1800 to 2100 h. Dialysates...
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