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In individuals with chronic kidney disease (CKD), treatment of elevated systolic blood pressure (SBP) is a key element in preventing disease progression and occurrence of cardiovascular events. For a given stroke volume, increased arterial stiffness is a key determinant of SBP. Therefore, the relationships between large conduit arteries and kidney function have been extensively studied in different...
BackgroundArteriosclerosis is a pathological, structural (media vascular calcification) and physiological (modified vascular smooth vessel cells; increased arterial stiffness) alteration of the vessel wall. Through improved assessment methods (functional and imaging), it has become a well‐known phenomenon in recent decades. However, its clinical importance was underestimated until recently.
Materials...
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