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The purpose of this study was to develop a new biodegradable bone substitute materials consisting of synthesized hydroxyapatite (HAp) and Type I biodegradable honeycomb collagen sponge (HCS) composites. Apatite-coated Honeycomb collagen composite scaffolds (HAp-HCS) was fabricated and the proliferation and differentiation of MC 3T3-E1 cells were examined for the assessment of their biocompatibility...
Hard tissue engineering has emerged to compensate for the losses in the properties of damaged bones by using scaffolds and cells. In this study, natural polymers chitosan and gelatin were used as scaffold materials because of their great resemblance to extracellular matrix elements. To enhance the mechanical properties and osteoconductivity of structures hydroxyapatite was added. This study is about...
Chitosan-Hydroxyapatite (Cs-Hap) composites were prepared through a biomimetic method by Hap precipitation from its precursors, CaCl2 and NaH2PO4, on the chitosan fibres. Materials composition and structure have been analyzed by usual analytical techniques, Fourier transform infrared spectroscopy (FT-IR) and scanning electron microscopy (SEM). FT-IR and SEM data have shown the formation of Hap onto...
Hydroxyapatite (HA,Ca10(PO4)6(OH)2), that the principal mineral component of the bone tissue, has remarkable precursor of growth properties in the porous structure sort with strongly interconnected pores. The interconnection of the pores is an essential condition assuring high quality of bone implants. We suggest the experimentation of a silicon nanotubes structure (SiNT) as support to enhance the...
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