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This paper presents various aspects of a double gate field effect transistor based nano biosensor. It addresses the performance in detecting Human Epididymis Protein 4 (HE4) which is a key biomarker for detecting ovarian cancer. At first a double gate FET was designed and different parameters of HE4 protein was calculated. Various nano biosensor characteristics in terms of settling time, selectivity...
Label-free electrical detection of avian influenza (AI) is demonstrated for the development of a point-of-care testing (POCT) platform. For a new POCT platform, a novel field effect transistor (FET)-based biosensor array was fabricated with conventional complementary metal-oxide-semiconductor (CMOS) technology. Nanogap-embedded separated double-gate FETs (nanogap-DGFETs) were realized in a 6×6 array...
Bio-detection specially dedicated to distributed diagnostics is emerging as a quite important application for Nano-bioelectronics. Bio-detection is required to be highly sensitive in order to succeed in sensing small amount of bio-markers in patient's blood sample. Carbon Nanotubes (CNTs) provides devices in the scale of the target molecules, thereby opening up possibilities to sense few bio-markers...
This work describes a label free, potentiometric method to detect cell surface sialic acid (SA) using phenylboronic acid (PBA) compound integrated into the form of self-assembled monolayer (SAM) on a field effect transistor (FET) extended gold gate electrode. Due to predominant binding between undisassociated PBA and SA at pH 7.4, we found that carboxyl anions of SA were exclusively detectable among...
Gateless AlGaN/GaN high electron mobility transistors (HEMTs) has some advantages include rapid response, low noise, and superior sensitivity. In different Al content, the Al0.3Ga0.7N has the excellent performance among Al0.17Ga0.83N and Al0.25Ga0.75N, and the performance can be achieved about -0.923 mA/mm-pH during pH 4-10, and -2.24 mA/mm-pH during pH 7-8. The result indicates that the better performance...
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