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A bio array sensing system is newly composed utilizing different phospholipid liposomes encapsulating fluorescent molecules. We have confirmed a high output intensity of fluorescence emission due to the characteristics dependent on the concentration of fluorescent molecules when the fluorescent molecules leak from inside of the liposome through perturbed lipid membrane. After measuring a whole array...
In this paper, we report a membrane filter-based detection system of bacteria using streptavidin functionalized quantum dots (SA-QDs) as a fluorescent probe. The aimed E. coli cells were marked by quantum dots through immuno-recognition, and then the marked bacteria were enriched by a low-fluorescence optical aluminium oxide membrane. A portable system was prepared for measurement of fluorescence...
Cardiac optical mapping changes cardiac membrane potential into optical signal with the voltage-sensitive dye, and carrys out image acquisition, storage, processing and other functions. This paper successfully finish image processing of the rabbit heart based on optical mapping, displaying membrane potential conduction map, denoising single-cell action potential duration map, locating the beginning...
Functional gel-nanotool impregnated with indicators for intracellular measurement in a microfluidic chip was developed. We employed membrane fusion of liposome for invasive injection of the gel-nanotool into a specific cell. The gel-nanotool is made by photo polymerization of the aggregated hydrophilic photo-crosslinkable resin. And it is modified by fluorescent dye for environment measurement. For...
A miniaturized fluorescence sensing system, incorporating proximal stacking of an LED, excitation filter and cell culturing substrate, is effective in imaging GT1-7 mouse hypothalamic neurons, and probing chemically induced changes in membrane potential.
Extracorporeal blood purification by means of the adsorption system MDS is based on high specific microparticle adsorbent for toxin removal. A thin-wall hollow-fiber membrane filter separates the microparticle-plasma suspension from the bloodstream. For patient safety, it is necessary to have a means to detect membrane ruptures that could lead to a release of microparticles into the patient's bloodstream...
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