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Many drugs used in the therapeutic regimen for various ailments undergo metabolism via cytochrome P450 1A2 (CYP1A2), so the agents or conditions altering the expression and/or activity of this enzyme play a significant role in therapeutic efficacy/failure of its substrates. Though curcumin is reported to be an inhibitor of CYP1A2, influence of curcumin on the pharmacokinetics of CYP1A2 probe phenacetin...
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