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We studied the dynamics of blood pressure and heart rate fluctuations during a head-up tilt testing in 127 patients and healthy individuals. To assess the regulation efficiency, in addition to the conventionally measured baroreflex sensitivity BRS, we also studied the stochastic phase synchronization coefficient Sync between short-term variations of the blood pressure and the heart rate estimated...
Autonomic nervous system dysfunction is common in patients with chronic kidney disease (CKD) and is associated with adverse cardiovascular (CV) outcomes and mortality in non-CKD populations, but has not previously been shown to predict all cause mortality in CKD. 134 patients were recruited to an observational study. CV structure, function and inflammatory status were quantified. Survival was assessed...
Cardiac autonomic neuropathy is a common complication in insulin dependent diabetes mellitus. Nevertheless, little is known about when this impairment occurs during the time course of the disease. Analysis of blood pressure (BP) and heart rate (HR) variability could be used to detect early signs of autonomic alteration. To test this proposal, twelve sexually mature male Yucatan miniature pigs were...
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