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ObjectivesRapid advances in genetic research and increased use of genetic testing have increased the emphasis on genetic causes of epilepsy in patient encounters. Research in other disorders suggests that genetic causal attributions can influence patients' psychological responses and coping strategies, but little is known about how epilepsy patients and their relatives will respond to genetic attributions...
Background Overlapping relationships among migraine, epilepsy and major depression have been identified in both cross-sectional case–control and prospective studies. Clinical and neurophysiological examination of such comorbidity can illuminate shared pathophysiology, and can have profound implications for diagnosis, prognosis, and treatment. Methods During the period of January 2013 through July...
Purpose: Depression is the most common comorbid condition in epilepsy. The cause of this comorbidity is unknown, and could involve psychosocial consequences of epilepsy, treatment side effects, seizure manifestations, or common neurobiologic mechanisms. One hypothesis of particular interest is a shared genetic susceptibility to epilepsy and depression. We tested this hypothesis by studying depressive...
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