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Circadian rhythms are biological processes found in all living organisms, from plants to insects to mammals that repeat with a period close to, but not exactly, 24 hours. In the absence of environmental cues, circadian rhythms oscillate with a period slightly longer or shorter than 24 hours. The 24-hour patterns of light and dark are the strongest synchronizer of circadian rhythms to the solar day...
Clinical research suggests that changes in the retinal blood vessels (e.g., vessel caliber) are important indicators for earlier diagnosis of diabetes and cardiovascular diseases. Reliable vessel detection or segmentation is a prerequisite for quantifiable retinal blood vessel analysis for predicting these diseases. However, the segmentation of blood vessels is complicated by its huge variations such...
Improving risk assessment to provide evidence for preventative intervention has recently become more of a focus in cardiovascular medicine with atherosclerosis as an early manifestation of cardiovascular disease. The total cholesterol to high-density lipoprotein (TC/HDL) ratio is often used an atherogenic index. High levels of the TC/HDL ratio also affect nervous system function and this study investigated...
Type 2 Diabetes Mellitus (DM), or adult-onset diabetes, is being considered as a new pandemia. Cardiovascular disease is the major cause of morbidity and mortality in type 2 DM, due to arterial structure and function changes. Assessment of arterial structure and biomechanics, by non-invasive methods and parameters, can be used to detect early alterations related to DM.
Globally, cardiovascular disease is the world's leading killer and is projected to remain so. The physiological signal variabilities, such as heart rate variability and pulse transit time variability, are useful indices to assess cardiovascular system function. The largest Lyapunov Exponent is used in this paper to analyze the physiological signal variability in cardiovascular system. Eight healthy...
The advances of high throughput research in the biomedical domain have resulted in an onslaught of data being generated at an exponential rate. As a result, researchers face challenges in navigating through overwhelming amounts of information in order to derive relevant scientific insights. Ontologies address these issues by providing explicit description of biomedical entities and a platform for...
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