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Glutamate-induced delayed calcium dysregulation (DCD) is a causal factor leading to neuronal death. The mechanism of DCD is not clear but Ca 2+ influx via N-methyl-d-aspartate receptors (NMDAR) and/or the reverse plasmalemmal Na + /Ca 2+ exchanger (NCX rev ) could be involved in DCD. However, the extent to which NMDAR and NCX rev contribute to glutamate-induced...
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