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The effectiveness and safety of various antipsychotics was evaluated in a long-term study on 47 patients, 29 with schizophrenia and 18 with schizoaffective disorder, aged 10 to 17years (mean 15.5) at onset. Follow-up ranged from 3years (all 47 patients) to 11years (19 patients). Data were collected on the following antipsychotics: haloperidol, risperidone, olanzapine, quetiapine, aripiprazole and...
Schizophrenia in children and adolescents is a devastating condition requiring urgent and aggressive treatment. However, the evidence base for the efficacy and safety of antipsychotic drugs is limited in this age group. Children and adolescents are particularly sensitive to developing severe, acute dystonic reactions with high potency typical antipsychotics such as haloperidol. Atypical antipsychotics;...
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