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Rapid development in technology and society has generated diverse developments in many fields including biosensors in healthcare application. Here, the design of integrated biosensor comprises mass sensing (Quartz Crystal Microbalance) and electrochemistry sensing (Electrochemical Impedance Spectroscopy, EIS and Cyclic Voltammetry, CV) will be presented. The integrated sensor system is developed based...
In recent years, quartz crystal microbalance (QCM) plays an important role in many biological detections, and the enhancement of a single strain DNA probe linked to the sensor surface is of crucial importance in DNA molecule recognition. By means of nanogold modification and mass amplification, a QCM biosensor for Escherichia coli O157:H7 DNA detection was explored and developed in this work. As a...
The hybridization of large DNA molecules has been investigated using quartz crystal microbalance (QCM) and electrochemical impedance spectroscopy (EIS). 20-base DNA probes bearing thiol groups were immobilized on the gold-quartz surface and gold electrode. Confirmation of this irreversible surface modification was obtained using cyclic voltammetry (CV). After the immobilization step, the probe was...
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