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A system to control the differentiation of human mesenchymal stem cells (hMSCs) using RNAi methods is being investigated. Through this delivery system, we aim to induce the differentiation of stem cells for a variety of regenerative medicine applications. In these preliminary studies, we have characterized both the cytotoxicity and uptake of our polymeric system relative to commercial siRNA delivery...
Epidermal stem cells have the characteristic of the undifferentiated cells in the morphology, and are the biological source of the skin and its subsidiary in the development, repair and reconstruction. The proliferation and differentiation of epidermal stem cell are influenced by many factors, such as integrin, signal transduction pathway and cytokines. Current researches have not yet been able to...
To explore the difference of gene expression in rat mesenchymal stem cell (MSC) and in the hippocampus of the Alzheimerpsilas disease (AD) model rats on Natural Brain-Kinetine by Gene chips. Methods: Rat MSC is primary cultured according to method-routie. The MSCs have two groups, the control group and treatment group without or with Natural Brain-Kinetine (NBK) respectively. MSCs gene expression...
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