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Several biological effects have been reported for mechanical forces on individual cells including: signal transduction, gene expression, growth, and differentiation. In this paper, a novel model for studying the cell behavior under the effect of stresses is developed. A well-defined fluid flow passing over a single cell fixed inside a microchannel is considered in this model. By multi-scale modeling...
We report the utilization of radial basis function neural networks (RBFNN) with multi-quadric (MQ) and inverse multi-quadric (IMQ) basis functions for numerical simulation of velocity-field reconstruction in fluid-structure interaction (FSI) problem with the presence of a very step velocity jump at the fluid-solid interface. The NN models were developed and utilized as approaches of investigation...
The effects of blockage due to a large particle suspended in the flow within a tube and rheological characteristics of the carrier fluid on fluid-particle conjugate heat transfer are investigated through computational fluid dynamics simulations. Case studies involving the aseptic processing of a spherical object immersed in pseudoplastic fluids of different power law indices were investigated numerically...
The purpose of this paper is to numerically analyze the three-dimensional fluid motion and temperature distribution in built-in motorized high-speed spindle housing having axial water cooling channel with rectangular crossection. A three dimensional finite element model of high speed spindle housing is developed and simulated using computational fluid dynamics software to determine the temperature...
Based on computational fluid dynamic (CFD) method, flow field analysis and structural optimization of a three-phase hydrocyclone were carried out by using FLUENT soft pack. By numerical simulation analysis on de-gas and de-sand functions of the three-phase hydrocyclone, effect of different geometric parameters on de-gas and de-sand functions is studied. It is found that the change of overflow tube...
Media perfusion bioreactor systems have been developed to culture tissue cells throughout 3D tissue engineered scaffold in vitro, which enhance the exchange of nutrients and wastes and deliver flow-mediated shear stresses to cells. Stress and strain field acting on the engineered cells is the outcome of several factors, such as characterization of the scaffold, medium flow rate and the interaction...
This paper introduces a new computational technique-solid cellular automaton-for the solution of physical field. The thought of cellular automaton comes from the self-organization theory in biology. In this theory, the state of a cell is determined by the states of itself and its neighbors. The information outside the neighbor domain does not contribute to the state of the cell. The global analysis...
In the paper, a numerical modelling of the air-flow in a high-speed permanent-magnet electrical machine is presented. The method couples computational fluid dynamics and heat-transfer equations in order to estimate the turbulent and thermal properties of the flow. The machine under consideration is a high-speed PM motor that is designed for speed n = 31500 rpm and power P = 130 kW. The geometry of...
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