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Artificial Biomolecular Condensates
In article number 2104704, Huaimin Wang and co‐workers report a general approach for constructing artificial biomolecular condensates of oligopeptide in living cells. The rationally designed aromatic‐capped peptides can reversibly form a nanofibrous hydrogel with a change of the conformation and morphologies in the lysosome. The formed condensates undergo swelling...
Biomolecular condensates have been demonstrated as a ubiquitous phenomenon in biological systems and play a crucial role in controlling cellular functions. However, the spatiotemporal construction of artificial biomolecular condensates with functions remains challenging and has been less explored. Herein, a general approach is reported to construct biomolecular condensates (e.g., hydrogel) in the...
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