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The detection and quantification of protein on a laser written flexible substrate for point-of-care applications are described. A unique way of etching gold on polyethylene terephthalate (PET) substrate is demonstrated by reducing the damage that may be caused on PET sheets otherwise. On the basis of the quantity of the C-reactive protein (CRP) present in the sample, the risk of cardiac disease can...
Surface based analytical tools have gained more importance for rapid, sensitive and label-free monitoring of molecular recognition events. Surface plasmon resonance (SPR) has played a prominent role in real time monitoring of surface binding events. SPR is increasing its significance especially for the study of ultrathin dielectric layer. This paper investigates the role of thin films of gold, silver...
Gold nanoparticle colorimetry assay using aptamers is a low cost and a highly effective means for detecting a wide range of biomolecular targets. In this work, this technique is used to detect the protein thrombin as a model system for understanding the relationship between the aptamer-target binding properties and the optical colorimetric response, as well as to gain insight on the secondary structures...
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