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Perioperative chemotherapy plus surgery improves survival compared to surgery alone in GE junctional (GEJ) and gastric adenocarcinomas. The docetaxel/cisplatin/5-fluorouracil (DCF) combination is superior to CF in patients with metastatic gastric cancer. We retrospectively evaluated the safety and efficacy of preoperative DCF chemotherapy in patients with locally advanced gastric and GEJ cancer. Twenty-one...
BACKGROUND:Docetaxel, cisplatin, and 5‐flurouracil (DCF) administered every 3 weeks produces a high rate of treatment‐related adverse events. The objective of the current study was to evaluate the efficacy and tolerability of a weekly formulation of DCF.
METHODS:Data from 117 patients treated at The University of Texas M. D. Anderson Cancer Center from 2002 to 2006 with a weekly formulation of DCF...
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