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Purpose
To prospectively investigate age‐ and gender‐related changes in the fast‐twitch (tibialis anterior, TA) and slow‐twitch (soleus, SOL) skeletal muscle of healthy rats and volunteers and to compare the exercise‐related difference in health volunteers with T1ρ magnetic resonance imaging (MRI).
Materials and Methods
In all, 18 rats and 70 humans were involved in this study. For the animal study,...
Background: Circulating metalloproteinases (MMP) and their inhibitors (TIMP) are indices of vascular and cardiac tissue matrix turnover. However, the temporal changes and relationship of these parameters to age, gender, ethnicity and exercise have been poorly defined. We therefore studied these aspects on plasma levels of MMP-2 and -9 and TIMP-1 and -2, as the major metalloproteinases (and their inhibitors)...
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