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The prediction of T-cell epitopes is of great help for facilitating vaccine design and understanding the immune system. In the bioinformatics, the MHC-binding peptides are defined as the T-cell epitopes, which will trigger the immune response to the antigens. However, binding peptides cannot necessarily activate the immune response, namely non-immunogenic. Until now, little attention has been paid...
Committee machines approach has shown to be useful in different applications. Protein primary structure data contain valuable information to extract. In this paper we mine these data and predict protein contact map based on committee machines. Contact map is the simplified, two dimensional representation of protein spatial structure. Contact map prediction is of great interest due to its application...
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