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Accurate spatial correspondence between template and subject images is a crucial step in neuroimaging studies and clinical applications like stereotactic neurosurgery. In the absence of a robust quantitative approach, we sought to propose and validate a set of point landmarks, anatomical fiducials (AFIDs), that could be quickly, accurately, and reliably placed on magnetic resonance images of the human...
There is growing evidence that sub‐structures of the brain scale allometrically to total brain size, that is, in a non‐proportional and non‐linear way. Here, scaling of different volumes of interest (VOI) to intra‐cranial volume (ICV) was examined. It was assessed whether scaling was allometric or isometric and whether scaling coefficients significantly differed from each other. We also tested to...
Functional and structural neuroimaging studies of major depression disorder (MDD) have identified neurophysiologic abnormalities in multiple areas of the prefrontal cortex, the insula, the amygdale and the related parts of the striatum and thalamus. The functional knowledge of MDD was mainly obtained from the fMRI and PET studies, which reveal the local differences in blood oxygenation and metabolism...
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