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The mammalian brain is a highly complex system with levels of organization that extend from nucleotides to large networks that generate adaptive behavior. To test our understanding of brain function we need to assemble and model interactions across levels. We are doing this for a genetically diverse family of BXD strains. This family has been densely genotyped and phenotyped for thousands of brain-related...
This article reviews neuronal activity related to reward processing in primate and human brains. In the primate brain, neurophysiological methods provide a differentiated view of reward processing in a limited number of brain structures. Dopamine neurons respond to unpredictable rewards and produce a global reinforcement signal. Some neurons in the striatum also react to the expectation and detection...
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