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Cardiovascular disease due to atherosclerosis is the number one killer in the Western world, and threatens to become the major cause of morbidity and mortality worldwide. It is therefore paramount to develop non-invasive methods for the detection of high-risk, asymptomatic individuals before the onset of clinical symptoms or events. In the recent past, great strides have been made in the understanding...
Direct tissue infusion has emerged as a promising drug delivery method for treating diseases of the nervous system because the blood-brain or blood-spinal cord barriers are circumvented. Determination of the spatial distribution of therapeutic agents after infusion is important in evaluating the efficacy of treatment and optimizing infusion protocols. In this study, we provide a methodology to determine...
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