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Synaptosomal membrane Na + , K + -ATPase is inhibited by neurotensin, an effect which involves its high affinity receptor (NTS1) [López Ordieres MG, Rodríguez de Lores Arnaiz, G. Peptides 2000; 21:571–576.]. Herein, the effect of neurotensin on synaptosomal membrane Na + , K + -ATPase of rats 18 h after i.p. administration of antipsychotic haloperidol (2 mg/kg) or clozapine...
In vivo temporal electron paramagnetic resonance (EPR) imaging of the blood-brain barrier-permeable nitroxide radical, 3-methoxycarbonyl-2,2,5,5-tetramethylpyrrolidin-1-yloxy (PCAM), in the brain of rats was conducted following acute administration of risperidone (RSP) or haloperidol (HPD). The half-life of the signal intensity of PCAM was obtained from a selected area in the temporal EPR images....
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