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The identical physiological signal, which is measured by different sources, can not compare directly. In order to process the data further and analysis the impact of uncertainty, a method of electrophysiological data normalization is proposed. In this paper, Mahalanobis scaling method is applied to electrophysiological data normalization in order to reduce the differences between different instruments,...
The predominant therapy for peripheral nerve transection is anastomosis by suture. However, sutures have been known to lead to tissue inflammation, granulomas, and poor functional outcomes. While adhesives offer a promising alternative, fibrin-the predominant bio-glue-can transmit disease. Here we examine a photocrosslinkable chitosan hydrogel for use in surgical therapies for peripheral nerve injury...
Patch clamp is the gold standard technique for the electrophysiological analysis of neuronal cells, but despite its sensitivity it is very demanding on manual work and unfit to monitor more than a few cells at the same time. The final aim of the presented work is to create a patch clamp system suited to measure simultaneously the electrical activity of an adherent neuronal network. For this purpose...
To fully exploit the recording capabilities provided by current and future generations of multi-electrode arrays, some means to eliminate the residual charge and subsequent artifacts generated by stimulation protocols is required. Custom electronics can be used to achieve such goals, and by making them scalable, a large number of electrodes can be accessed in an experiment. In this work, we present...
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