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Understanding the initiation site and propagation of epileptiform discharges in hippocampus are of important physiological significance. Here in transverse plane of hippocampus, the above questions were investigated with low-Mg2+ ACSF perfused hippocampal slices of Sprague Dawley rat using microelectrode arrays. Initiation site of epileptiform discharges was determined by comparing the onset time...
Drug resistant epilepsy can in some cases be treated with surgery. To minimize potentially crippling side effects of surgery, a detailed functional map of the brain is usually required prior to resection. Conventional mapping techniques rely on a coarse grid of electrodes with limited spatial resolution. Ultrasound Current Source Density Imaging (UCSDI) is new high resolution method to image electric...
In this paper, we present a new kind of neural signal recording and stimulating system consisting of active microelectrode arrays, signal conditioning circuits and user interface. The system is designed to record from up to 32 sites of nervous system in 3-D dimension with good signal-to-noise ratio (SNR) and DC offset stabilization, which gives neurophysiologists better tools to understand neural...
The development of a 16 electrode-electrical impedance tomography (EIT) prototype to be applied in neurological fields such as epilepsy in rats has been previously reported. Approaching residual problems in order to improve its performance, this work reports results about changes made in the system hardware as follows: 1) replacing the current source demultiplexing circuit that could impact on a better...
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