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We developed a micro-TAS system that uses magnetic wires instead of the conventional beads as the carrier to improve reaction efficiency. Magnetic wire 2.0 mm×74 μm×20 μm was fabricated by wet etching. The wires were introduced into a droplet immersed in silicone oil, and they were manipulated by the magnetic force of a moving magnet. The wires were successfully bundled for transportation through...
Microfluidic systems are one of the new growing technologies which offer miniaturization of analysis systems. In this paper we present a simple and low cost fabrication of microchannels using in different applications in Micro Total Analysis Systems. This method uses typical microscopic glass slides as a substrate for fabrication of microchannels. Using photo-resist as a mask instead of some deposition...
This paper presents a mechanical cell lysis microfluidic chip with an ultra-sharp nano-blade array fabricated by simple and cost effective crystalline wet etching of (110) silicon. The ultra-sharp nano-blade array is simply formed by the undercutting during the crystalline wet etching process. The sharpness of the silicon nano-blade is less than 10 nm after the undercutting. EL4 mouse T-lymphoma cells...
In this study, we present a novel three-level pillars silicon master to fabricate the transparent polydimethylsiloxane (PDMS) biochip with 1 ??m aperture. The three-level pillars silicon master was manufactured by photolithography and ICP etching processes. Especially, we use the IR (image reversal) mode to fabricate the third pillar in silicon master for increasing the successful rate. Due to the...
A rapid prototyping method was developed to integrate a microfluidic plasma separation device over a Si based radiation detector. KMPR photoresist was used to produce high pressure resistant channels sealed by a glass cover. Two methods were investigated to make access holes in the cover: laser micromachining and a simplified glass wet etching process. The lab-on-chip concept where a plasma separation...
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