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Hepatic Steatosis (HS) or Fatty Liver is a disease due to fat accumulation within hepatocytes. This disease requires treatment to avoid clinical complications such as hepatic inflammation, fibrosis and finally chronic hepatic damage and hepatic carcinoma. An algorithm for performing the manual segmentation was used. A polygon is traced for representing the region of interest in tomography (CT) images...
Sepsis is the leading cause of death in critically ill patients in the United States. Current diagnosis of sepsis relies heavily on the patient's manifestation of septic symptoms, which occur at life-threatening late stage of sepsis. Because the underlying biological changes of sepsis occur hours to days before the clinical presentation of symptoms, early detection of the biological changes will provide...
Clinical diagnosis and quantification of liver disease have been improved through the development of techniques using contrast-enhanced liver MRI sequences. To qualitatively or quantitatively analyze such image sequences, one first needs to correct for rigid and non-rigid motion of the liver. For motion correction of the liver, we have employed bi-directional local correlation coefficient Demons,...
Sepsis is the leading cause of death in critically ill patients in the United States. Current diagnosis of sepsis relies heavily on the patient's manifestation of septic symptoms, which occur at life-threatening late stage of sepsis. Because the underlying biological changes of sepsis occur hours to days before the clinical presentation of symptoms, early detection of the biological changes will provide...
In this study, Mn-dipyridoxaldiphosphate (MnDPDP), a clinically approved manganese contrast agent for hepatic and pancreatic imaging, was demonstrated for the first time for manganese-enhanced MRI (MEMRI) in brains of normal young rats (n = 3D4) and rats with hypoxic-ischemic (H-I) insult at postnatal day 7 (n = 3D8). After a single intraperitoneal injection of low dosage with 0.1 mumol/g in postnatal...
In this paper, the classification of liver diseases using first-order statistics (FOS) is implemented for automatic preliminary diagnosis of liver diseases. Region of interest (ROI) extracted from MRI images are used as the input to characterize different tissue, namely liver cyst, fatty liver and healthy liver using first-order statistics. The results for first-order statistics are given and their...
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