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Based on the clinical date of the Peginterferon Alfa-2a plus Lamivudine (combination therapy) for HBeAg-Positive chronic hepatitis B patients, this paper sets up a mathematical model consisting of two differential equation systems that enable us to describe and understand the dynamics of host cells, virus and the immune system. Our model provide a possible interpretation for the effect of combination...
Abnormal functioning of different organs such as pancreas, liver and/or body tissues can result in excessive blood glucose concentration in type II diabetic patients. Although a number of models have been developed for evaluating type I diabetes mellitus, there is limited evaluation for patients with type II. This paper presents the development of a model for type II diabetic patients based on a detailed...
A hybrid model is developed by integrating a case-based reasoning approach and a particle swarm optimization model for medical data classification. The data sets from UCI Machine Learning Repository; Liver Disorders Data Set is employed for benchmark test. Initially a case-based reasoning method is applied to preprocess the data set thus a weight vector for each feature is derived. A particle swarm...
Based on a patient's anti-hepatitis B virus (HBV) infection therapy clinical data of a new type of Chinese herbs (NTCH, consisting of 13 ingredients) plus adefovir dipivoxil, and our previous modified basic virus infection model [1], a new differential equation model with an immune variable is set up, and aims to describe and understand the dynamics of host cells, viruses, the immune system, as well...
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