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The single isomer drug R,R-tadalafil (Cialis ® ) contains two chiral centers thus four stereoisomers (R,R-, S,S-, S,R- and R,S-tadalafil) exist, however, only the most potent inhibitor, the R,R-tadalafil is in clinical use.In our study, over 20 charged cyclodextrin (CD) derivatives were studied for enantiospecific host–guest type interactions in CD-modified capillary electrophoresis. Tadalafil...
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