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Chitosan-Hydroxyapatite (Cs-Hap) composites were prepared through a biomimetic method by Hap precipitation from its precursors, CaCl2 and NaH2PO4, on the chitosan fibres. Materials composition and structure have been analyzed by usual analytical techniques, Fourier transform infrared spectroscopy (FT-IR) and scanning electron microscopy (SEM). FT-IR and SEM data have shown the formation of Hap onto...
Calcium phosphate cement (CPC) sets in situ to form hydroxyapatite and is highly promising for a wide range of clinical applications. However, its low strength limits its use to only non-stress applications, and its lack of macroporosity hinders cell infiltration, bone ingrowth and implant fixation. The aim of this study was to develop strong and macroporous CPC scaffolds by incorporating chitosan...
Biodegradable polymer-ceramic composite scaffolds have gained importance in recent years in the field of orthopedic biomaterials and tissue engineering scaffolds in order to improve limited mechanical properties of bioactive ceramics. In this study, electrospun composites consisting of 20%hydroxyapatite/80%szlig-tricalciumphosphate and poly(epsiv-caprolactone) were fabricated. For electrospinning,...
The purpose of this study was to prepare a 3D nanocomposite bone substitute prepared from gelatin (GEL) and synthesized hydroxyapatite (HAP) in order to mimic natural bone feathers through a novel layer solvent casting combined freeze-drying technique. The adhesion between superimposed layers was ensured by applying a GEL solution. Furthermore, samples were cross-linked with 1% glutaraldehyde (GA)...
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