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Aim of this study was to provide a proof-of-principle for a neurofeedback-based cognitive telerehabilitation system. Here we describe the implementation of the system and its application and evaluation in two neurological patients with multiple sclerosis suffering from cognitive deficits. The portable telerehabilitation system consists of a small EEG amplifier, an easy-to-use semi-dry EEG headset...
Cognitive impairment affects half of the multiple sclerosis (MS) patient population, is difficult to detect and requires extensive neuropsychological testing. We analyzed data obtained in a P300 experiment. The P300 is a large positive wave following an unexpected stimulus and is mainly related to attention, a domain frequently impaired in MS. Apart from the traditional features used in P300 experiments...
This paper presents our experience with developing a portable wireless medical sensor device. We use National Instruments (NI) devices and LabView for measurements studying fatigue of patients suffering multiple sclerosis (MS). Fatigue is a very frequent symptom perceived by MS patients, but the disease mechanism is poorly understood. Many efforts have been made to increase the understanding of this...
A multiplexing, multimarker protein immunosensor based upon electrochemical impedance spectroscopy was designed, fabricated, and analyzed. The antibody based molecular recognition element sensor was demonstrated using five inflammatory cytokines and receptors . These pro- and anti-inflammatory markers are used in cellular signaling and could be useful in early detection of diseases including multiple...
Intraspinal microstimulation is a neuroprosthetic approach for activating specific spinal reflexes using penetrating electrodes chronically implanted into spinal cord. Artificial control of spinally mediated functions, such as arm and leg movement or bladder voiding, may be necessary in spinal cord injury, multiple sclerosis, cerebral palsy, amyotrophic lateral sclerosis, and spina bifida, when the...
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