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Studying intracellular dynamics is of major importance for understanding healthy life at the molecular level and for developing drugs to target disease processes. One of the key technologies to enable this research is the automated tracking and motion analysis of subcellular objects in microscopy image sequences. Contrary to common frame-by-frame tracking methods, two alternative approaches have been...
Live-Cell Assays are used to study the dynamic functional cellular processes in high-content screening of drug discovery processes. One class of tasks in this application is the tracking of cells and the description of the events and the changes in the cell characteristics. The large amount of data requires fast processing algorithms and compact object and event descriptions. We propose in this paper...
Laser scanning confocal technology was used to study relationship between apoptosis and changes of Ca2+ induced by CSA (Capparis spinosa L. total alkaloid, CSA) on human heptocarcinoma cell HepG-2. Killing effects of CSA on human heptocarcinoma cell HepG-2 was measured by MTT method, while morphological observation on HepG-2 cells was completed by fluorescence microscope. Apoptosis of HepG-2 cells...
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