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In this paper, we proposed a novel method of signal quality assessment of arterial blood pressure for monitoring Cerebral Autoregulation (CA). This method is based on algorithm of signal abnormality index (SAI). Two simple and effective features-end diastole slope sum (EDSS) and slow ejection slope sum (SESS), were proposed to identify abnormal beats from ABP as CA input in real-time. The methods...
The need of continuous blood pressure measurement is usable in wide spectrum of applications from physicians practice to home care applications. Many types of blood pressure measurement devices can be bought in electronics shops. All such devices are contact measurement devices which need to be in contact of human body (hand or foot mainly). Secondary they allow only one measurement per several minutes...
We propose that the computation of the AIS (Augmentation Index Series) and TIS (Time Interval Series) from continuous arterial pressure signals, can be useful tools in the evaluation of arterial and cardiac pathologies.
Pulse wave velocity (PWV) is a marker of arterial stiffness and may permit continuous, non-invasive, and cuff-less monitoring of blood pressure. Here, robust PWV estimation was sought by application of system identification to proximal and distal arterial waveforms. In this approach, the system that optimally couples the proximal waveform to the distal waveform is identified, and the time delay of...
Cardiac output (CO) and stroke volume (SV) are the key hemodynamic parameters to be monitored and assessed in ambulatory and critically ill patients. The purpose of this study was to introduce and validate a new algorithm to continuously estimate, within a proportionality constant, CO and SV by means of mathematical analysis of peripheral arterial blood pressure (ABP) waveforms. The algorithm combines...
We recently proposed a technique to estimate relative cardiac output (CO) change by unique long time interval analysis (LTIA) of a radial arterial blood pressure waveform. Here, we evaluated the technique in 169 critically ill patients, while comparing it to previous “pulse contour analysis” techniques, using the public MIMIC II database. The LTIA technique achieved an overall calibrated CO error...
The Pulse Transit Time (PTT) is generally assumed to be a good surrogate measure to comfortably track blood pressure (BP) and blood pressure changes. This paper investigates PTT variations for healthy young subjects during a sequence of short-term physical exercises. PTT was measured by two different methodologies having different measurement accuracies as well as underlying assumptions: the total...
Monitoring cardiac output (CO) is important for the management of patient circulation in an operation room (OR) or intensive care unit (ICU). We assumed that the change in pulse wave transit time (PWTT) obtained from an electrocardiogram (ECG) and a pulse oximeter wave is correlated with the change in stroke volume (SV), from which CO is derived. The present study reports the verification of this...
In developing a wrist blood pressure monitor of high and reliable accuracy, the effect of different pressurization methods on the accuracy of blood pressure measurement at the wrist using oscillometry is investigated in this paper. 30 volunteers are recruited and blood pressure readings are taken with three different methods of pressurizing the wrist. It was found that measurement of mean arterial...
A novel, wireless, batteryless, implantable blood pressure monitoring microsystem for small laboratory animals is developed for advanced biological and system biology research. The system employs an instrumented elastic circular cuff, wrapped around a blood vessel, for real-time blood pressure monitoring. The elastic circular cuff is made of soft bio-compatible silicone material, which is filled with...
Two novel, wireless, batteryless, less-invasive blood pressure sensing microsystems based on circular cuff and flat cuff configurations are developed for advanced biomedical application. Both systems employ an instrumented silicone cuff, wrapped around a blood vessel, for real-time blood pressure monitoring. The cuff is filled by silicone gel with an immersed MEMS pressure sensor and integrated electronic...
A new cuff unit for measuring instantaneous blood pressure at the finger based on the volume-compensation method by local pressurization is developed, and its characteristics are evaluated. Results of measurement indicated that, the finger artery could be completely compressed using the local pressurization cuff, and the cuff-pressure controller is suitable for BP measurement in human. Also, the comparative...
An instantaneous blood pressure measuring system at the wrist based on the volume-compensation method is developed, and the characteristics and accuracy of the system are evaluated. Results of measurement indicated that, the radial artery could be completely compressed using the local pressurizing cuff, and the cuff-pressure controller is suitable for BP measurement in human. Also, the comparative...
A novel implantable sensor for continuous long-term monitoring of various cardiovascular parameters is presented. An optical arterial blood oxygen saturation sensor and a piezoelectric blood pressure sensor have been developed using a silicone-based fabrication technology. An elastic silicone stripe houses the sensors and is wrapped around an arterial blood vessel. Due to this choice of a soft material,...
We propose a wavelet-based spectral density estimation method for characterizing pulse rate variability of short duration oscillometric blood pressure signals produced by a digital blood pressure monitor during routine measurements. To validate our wavelet metric we compare its performance with other techniques by studying correlations of pulse rate variability with age and mean arterial pressure...
The objective of this article is to evaluate the relationship between coronary artery calcification (CAC) and arterial compliance for patients with different calcification scores. Sixty one patients under went coronary artery calcification examination were recurred for this study. Patients were divided into three groups: low-score (0~11), mid-score (11~100) and high-score (101~), according to their...
A novel wireless less-invasive implantable blood pressure sensing system is developed for advanced biological research. The system employs a miniature instrumented elastic cuff, wrapped around a blood vessel, for small animal real time blood pressure monitoring. The elastic cuff is made of biocompatible soft silicone material by a molding process and is filled by insulating silicone oil with an immersed...
A diaphragm-type optical fiber pressure sensor, which has a sleeve for fiber insertion, is proposed, and its fundamental characteristics are demonstrated. The sleeve structure is fabricated by deep reactive ion etching (DRIE). The diaphragm with the sleeve is suitable for highly reliable and easy bonding between the sleeve and an optical fiber. The light intensity change by a Fabry-Perot interferometer...
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