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The aging process is a complex biological phenomenon that can be attributed to several mechanisms. ROS (reactive oxygen species) activity is widely considered one of them, as it is associated with extensive damage in a variety of cells. For example, the gradual decrease in fertility often accompanying aging males can be traced back to oxidative stress, since ROS are released throughout life from the...
Comparative studies about the relationship between endogenous antioxidant and pro-oxidant factors and maximum longevity of different animal species are reviewed. The majority of studies on antioxidant supplementation indicate that it can increase mean survival without changing maximum longevity. On the other hand, endogenous antioxidants are negatively correlated with maximum longevity. The same is...
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