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A peptide hydrogel for in vitro culture of chondrocytes was prepared and investigated based on the designed and synthesised peptide SGGAGGAGGAGGAGGS. Chondrocytes cultured in the peptide hydrogels were observed for changes of morphology characteristic, and the chondrocyte-seeded peptide hydrogels at the designed time point were obtained and the analysis of DNA content, histological staining and immuno-histochemistry...
This paper describes a hydrogel microfiber encapsulating bacteria using an axisymmetric microfluidic device that creates co-axial laminar flow. Since the encapsulated bacteria proliferate at high density in the core of the microfiber, they easily form biofilms; these films are suggested to be important for the cell viability and high-level bacterial secretion. Here, we succeeded in preparing densely...
Utilization of enzyme catalysis as a tool to disassemble self-assembled hydrogels to control the release encapsulated drug provides an opportunity to design a wide range of enzyme-specific low-molecular-weight hydrogelators (LMWGs). Herein, we report a novel approach for controlled delivery of multiple drugs by an enzyme triggered hydrogel degradation mechanism. In this proof-of-concept work, we report...
Human embryonic germ (hEG) cells have the potential to self-renew over long periods of time and differentiate into various lineages. Cells derived from embryoid bodies of hEG cells express a broad spectrum of gene markers and have been induced towards cells of ecto-dermal and recently endo-dermal and mesenchymal lineages. LVEC cells express a number of surface marker proteins characteristic of mesenchymal...
Human embryonic germ (hEG) cells have the potential to self-renew over long periods of time and differentiate into various lineages. Cells derived from embryoid bodies of hEG cells express a broad spectrum of gene markers and have been induced towards cells of ecto-dermal and recently endo-dermal and mesenchymal lineages. LVEC cells express a number of surface marker proteins characteristic of mesenchymal...
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